Advances in T cell transformation research to reduce rejection in organ transplantation

According to the Evening News, regulatory T cells (Tregs) play an important role in maintaining immune homeostasis and suppressing organ transplant rejection. Recently, the "Third International Conference on the Research Progress and Clinical Application of Treg / Helper T Cell Subgroups" was held in Shanghai. A recent study of Tongji University's Affiliated Oriental Hospital found that artificially cultured and induced regulatory T cells produce TGF- Cytokines such as beta and IL10 have played an important role in reducing human rejection after organ transplantation.

As a clinical medicine scientist, Professor Liu Zhongmin from the Oriental Hospital Affiliated to Tongji University said that their current research results show that T cells produced and induced in vitro not only have no side effects, but also interact with dendritic cells (DC) in the body. To achieve self-cloning and expansion of inducible T cells. By injecting and regulating induced T cells, scientists can not only get enough "ammunition" to suppress the rejection of grafts, but also gradually control the balance between T cells and other cells, and prevent diseases while treating them.

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