British developed "U disk" genome sequencer

British developed "U disk" genomic sequencer According to a recent report from the American Physicists Organization Network, Oxford Nanopore Technology of the United Kingdom announced an explosive news at the Florida Genomic Biology and Technology Conference, that is, the launch of GridION and MinION The next-generation DNA sequencing technology of portable genome sequencers, the latter is only the size of a U disk, can be inserted into a computer USB port to complete sequencing, the price is only 900 US dollars. Both instruments are based on nanopore sequencing technology, using a special protein to make nanoscale holes or pores in the membrane structure, and applying a voltage on one side of the membrane to pull a single DNA strand (negatively charged) into the nanopore. When the chemical bases of DNA pass through, a subtle current change is caused. By measuring this change, the sequence of different bases (T, C, G, and A) can be identified, and then the results of each part are woven together by a computer. Render. The human genome contains about 3 billion bases, and DNA sequencing is to read the order of these bases. The news made investors very excited, and it was like a big hit for the rivals of Oxford Nanopore Technology Inc., Illumina and Life Technologies. The latest bench-top ion proton sequencer sequencing launched by Life Technology Company at the beginning of this year took 24 hours and cost about US $ 150,000. In contrast, if 20 units are connected together, GridION can complete the entire human genome sequencing in 15 minutes, the price is 5,000 US dollars; such as U disk size, plug and play MinION can be directly plugged into the USB port of the laptop for sequencing . Undoubtedly, the new sequencer will bring more extensive applications of DNA sequencing, allowing non-professional scientists to extract DNA information. Even in the field, researchers can put samples in the instrument and insert them into a laptop computer with related software. Almost a moment you will get information on genomic samples to determine the genetic traits of plants or animals. Seed research companies can use it to analyze field crops, such as to check if there is an exogenous mix; meat inspectors can use it to test different types of microorganisms; biologists can use it to find small changes in the genes of generations. However, there are minor flaws in these visions: the current error rate of this device is 4%; MinION is one-time and the output is not as high as GridION; although the company claims that the price will be before the relevant products are released sometime this year Significant decline, but still expensive for many users.

Components

Components are a common window decoration that can effectively control light and ventilation. It consists of multiple independent horizontal or vertical rotatable lamellae, the angle of which can be adjusted by pull cord or manual operation to achieve the purpose of controlling light and privacy. Blinds usually consist of the following components:

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