According to a report by the BBC on July 31, a research team at the Scripps Institution of Oceanography at the University of California, San Diego, extracted a brand new rare compound from marine microorganisms deposited on the California coast, which can effectively kill resistant Bacteria with extremely strong antibiotics: anthrax and superbug MRSA. The detailed information of the research results was published in the latest issue of the German "Applied Chemistry" magazine.
Anthrax is caused by Bacillus anthracis, an acute infectious disease coexisting with humans and animals. People will be infected by contact with sick animals and their products or eating meat of sick animals; the super pathogen MRSA is methicillin-resistant golden yellow grapes Cocci are antibiotics and drugs that can cause various infections and resist the most powerful antibiotics, that is, they cannot be killed by using multiple antibiotics.
Recently, Thomas Frieden, director of the US Centers for Disease Control and Prevention, warned of the risks posed by antibiotic-resistant bacteria, and at the same time, British Chief Medical Officer Sally Davis described the bacteria as a threatening country A safe "time bomb". The American Society of Infectious Diseases is concerned that the development of antibiotic resistance against this bacterial resistance is not developing at a sufficient rate. Undoubtedly, this latest discovery is particularly welcome.
William Fanick, Distinguished Professor of Oceanography and Pharmaceutical Sciences at the Scripps Research Institute, said that we named this brand new, unusual compound anthracimycin, which has a unique chemical structure. Using various analysis methods, they found that anthrax toxin contains an unusual ring system, one ring contains 14 carbon atoms, and the other two rings each contain 6 carbon atoms. This macrolide may be biosynthesized through the polyketone pathway.
Unlike any previously reported natural antibiotics, new research may lead to the testing and development of a new antibiotic drug. Initial tests have shown that the new compound is effective against bacteria that have been feared as a biological weapon for anthrax. And it also showed significant activity against the superbug MRSA.
Fanike commented: "This discovery complements many previous researches that have shown that marine bacteria are unique in genetics and chemistry. The latest evidence provided by this study shows that the ocean and many of its untapped marine areas are The development of new materials and medicines for the treatment of various diseases is a potentially huge resource treasure. "
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